SCHEMBL5310798

SCHEMBL5310798

O=C(O)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMO O15229 4/20 1.00
TSHR P16473 1/20 0.53
SRD5A2 P31213 1/20 0.47
NFE2L2 Q16236 1/20 0.45
HPGD P15428 1/20 0.44
PKM P14618 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
LTC4S Q16873 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753610 1.00 KMO (1.00) KMOTSHRSRD5A2NFE2L2HPGD
SCHEMBL31060580 1.00 KMO (1.00) KMOTSHRSRD5A2NFE2L2HPGD
SCHEMBL21974233 1.00 KMO (1.00) KMOTSHRSRD5A2NFE2L2HPGD
SCHEMBL15337002 1.00 KMO (1.00) KMOTSHRSRD5A2NFE2L2HPGD
SCHEMBL16506215 0.85 KMO (0.74) KMOTSHRMEN1NPC1MAPT
SCHEMBL15319105 0.85 KMO (0.74) KMOHPGDMEN1NPC1MAPT
SCHEMBL16506378 0.85 KMO (0.74) KMOTSHRMAPTLTC4S
SCHEMBL16506208 0.85 KMO (0.74) KMOTSHRMEN1NPC1MAPT
SCHEMBL16506687 0.85 KMO (0.73) KMOTSHRSRD5A2NFE2L2HPGD
SCHEMBL12327668 0.83 KMO (0.71) KMOTSHRSRD5A2HPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345316-A1 METHODS OF INCREASING LYMPHOCYTE TRAFFICKING TO THE COLON BY STIMULATING RETINOIC ACID RECEPTORS AND ARYL HYDROCARBON RECEPTORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-11-13 US claimed
US-12280047-B2 Treatment of aneurysms GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2025-04-22 US claimed
CN-119485512-A Dynamic bandwidth capacity control for enterprises 慧与发展有限责任合伙企业 2025-02-18 CN claimed
CN-114674827-B Bridge crack detection method based on two-stage deep learning strategy 兰州交通大学 2024-09-20 CN claimed
CN-118485425-A Multi-fault rush-repair and recovery method for power distribution network containing distributed power supply 华北电力大学(保定) 2024-08-13 CN claimed
CN-117218821-A Networked prediction and cooperative control method and device for non-signal-control multi-intersection hybrid vehicle group 清华大学 2023-12-12 CN claimed
US-20230143415-A1 TREATMENT OF ANEURYSMS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2023-05-11 US claimed
US-11376248-B2 Treatment of aneurysms GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-05 US claimed
CN-114674827-A Bridge crack detection method based on two-stage deep learning strategy 兰州交通大学 2022-06-28 CN claimed
WO-2007054348-A1 NOVEL MEDICAMENTS Ernst-Moritz-Arndt-Universität Greifswald (DE) 2007-05-18 WO claimed
EP-4750039-A1 IN-NETWORK COMPUTING USING UPF ENHANCEMENT WITH EXPOSURE IN NEXT GENERATION CELLULAR NETWORKS INTEL Corporation (US) 2026-05-27 EP disclosed
US-12639711-B2 Transaction processing device, transaction processing method, and program recording medium TOSHIBA TEC KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-20260136341-A1 TECHNIQUES FOR DOWNLINK AND UPLINK RESOURCE MAPPING FOR FULL DUPLEX AND NON-CELL DEFINING SYNCHRONIZATION SIGNAL BLOCK INTEL CORP (US) 2026-05-14 US disclosed
CN-121619335-A Lightweight end cloud collaborative data acquisition method and system 岚图汽车科技股份有限公司 2026-03-06 CN disclosed
CN-121579227-A Enterprise digital platform data management method and system 深圳市思普达软件系统有限公司 2026-02-27 CN disclosed
US-20150057238-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. 2015-02-26 US disclosed
EP-2833879-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF CHDI Foundation, Inc. (US) 2015-02-11 EP disclosed
WO-2013151707-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. (US) 2013-10-10 WO disclosed
WO-2013151707-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF CHDI FOUNDATION, INC. (US) 2013-10-10 WO disclosed
WO-2007054348-A1 NOVEL MEDICAMENTS Ernst-Moritz-Arndt-Universität Greifswald (DE) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150057238-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF KMO, KYNU, AADAT KMO 1/4885TSHR 4002/4885SRD5A2 1029/4885
US-20230143415-A1 TREATMENT OF ANEURYSMS KYNU, HAAO, HCAR2 KMO 7/4885TSHR 4479/4885SRD5A2 2127/4885
US-20260136341-A1 TECHNIQUES FOR DOWNLINK AND UPLINK RESOURCE MAPPING FOR FULL DUPLEX AND NON-CELL DEFINING SYNCHRONIZATION SIGNAL BLOCK SNRPB2, FOSB, SMCHD1 KMO 3622/4885TSHR 2405/4885SRD5A2 2858/4885
US-12280047-B2 Treatment of aneurysms KYNU, HAAO, HCAR2 KMO 7/4885TSHR 4479/4885SRD5A2 2127/4885
US-11376248-B2 Treatment of aneurysms KYNU, HAAO, HCAR2 KMO 7/4885TSHR 4479/4885SRD5A2 2127/4885
US-12639711-B2 Transaction processing device, transaction processing method, and program recording medium TRRAP, TES, TMT1A KMO 2626/4885TSHR 206/4885SRD5A2 3899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.