Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313725 | 0.91 | KMT2A (0.51) | KMT2AMEN1ATMSLC40A1MAPT | |
| SCHEMBL5311729 | 0.86 | HCRTR1 (0.43) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL5313192 | 0.84 | PTGDR2 (0.48) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL5312227 | 0.83 | CCR4 (0.46) | HTTMAPT | |
| SCHEMBL5310476 | 0.79 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5314252 | 0.79 | PTGDR2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL5310070 | 0.78 | CA12 (0.43) | ALDH1A1MAPT | |
| SCHEMBL5311159 | 0.76 | PTGDR2 (0.49) | — | |
| SCHEMBL5311262 | 0.76 | PTGDR2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL5312658 | 0.76 | MAPT (0.51) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |