Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314252 | 0.92 | PTGDR2 (0.47) | MAPTPTGDR2AKR1B1FLT1FLT4 | |
| SCHEMBL5313125 | 0.91 | PTGDR2 (0.55) | SERPINE1PTGDR2AKR1B1FLT1FLT4 | |
| SCHEMBL5311262 | 0.89 | PTGDR2 (0.47) | MAPTPTGDR2AKR1B1CA12CA1 | |
| SCHEMBL5307807 | 0.88 | PTGDR2 (0.50) | MAPTPTGDR2AKR1B1FLT1FLT4 | |
| SCHEMBL5310476 | 0.87 | ALDH1A1 (0.46) | MAPTPTGDR2CA12CA1CA2 | |
| SCHEMBL5310070 | 0.86 | CA12 (0.43) | MAPTACLYPTGDR2AKR1B1FLT1 | |
| SCHEMBL5313784 | 0.86 | USP2 (0.45) | MAPTPTGDR2AKR1B1FLT1FLT4 | |
| SCHEMBL5307689 | 0.85 | PTGDR2 (0.46) | PTGDR2AKR1B1FLT1FLT4KDR | |
| SCHEMBL5313192 | 0.85 | PTGDR2 (0.48) | MAPTPTGDR2FLT1FLT4KDR | |
| SCHEMBL5310742 | 0.83 | PTGDR2 (0.60) | PTGDR2AKR1B1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |