SCHEMBL5310985

SCHEMBL5310985

CCc1ccc(C(=O)c2ccccc2)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.56
LTC4S Q16873 2/20 0.55
CDC25B P30305 2/20 0.54
CDC25A P30304 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KDM4E B2RXH2 1/20 0.53
METAP2 P50579 1/20 0.50
POLB P06746 2/20 0.49
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
ALDH1A1 P00352 3/20 0.47
TP53 P04637 1/20 0.46
HNF4A P41235 1/20 0.46
ATM Q13315 1/20 0.46
PTGS2 P35354 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27476186 0.93 KDM4E (0.62) AKR1C3LTC4SCDC25BCDC25AHSD17B10
SCHEMBL11233529 0.85 TP53 (0.47) AKR1C3LTC4SKDM4EPPARGPPARD
SCHEMBL22389564 0.85 PTGS2 (0.55) AKR1C3METAP2PPARGPPARDPPARA
SCHEMBL4733091 0.84 TSHR (0.53) CDC25BHSD17B10POLBPPARGPPARD
SCHEMBL28409934 0.84 AKR1C3 (0.49) AKR1C3LTC4SCDC25BCDC25AHSD17B10
SCHEMBL1287171 0.84 ALDH1A1 (0.54) CDC25BHSD17B10METAP2PPARAALDH1A1
SCHEMBL30070803 0.83 HNF4A (0.54) HSD17B10KDM4EPPARGPPARDPPARA
SCHEMBL4521629 0.83 HNF4A (0.54) HSD17B10KDM4EPPARGPPARDPPARA
SCHEMBL4604200 0.83 MEN1 (0.62) HSD17B10KDM4EPPARGPPARDPPARA
SCHEMBL10395912 0.83 MAPT (0.58) CDC25BHSD17B10KDM4EPOLBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044184-A1 WATER SOLUBLE PHOTOINITIATOR ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed
US-4163810-A Ultraviolet curable powder paints SCM CORPORATION (US) 1979-08-07 US disclosed
US-4129488-A Ultraviolet curable epoxy-polyester powder paints SCM CORPORATION (US) 1978-12-12 US disclosed
US-4105518-A POLYMER CONTAINING ACRYLYL, ACRYLAMIDE OR ALLYL UNSATURATED GROUPS, REACTED WITH SECONDARY AMINE AND NEUTRALIZED, SENSITIZER SCM CORPORATION (US) 1978-08-08 US disclosed
US-4052280-A PHOTOSENTIZER IN BACKBONE OF POLYMER SCM CORPORATION (US) 1977-10-04 US disclosed
US-4040925-A PAINTS; CHEMICALLY BONDED ULTRAVIOLET SENSITIZER SCM CORPORATION (US) 1977-08-09 US disclosed
US-4039414-A ACRYLYL, ACRYLAMIDE, OR ALLYL POLYMERS, BENZALDEHYDE SENSITIZER SCM CORPORATION (US) 1977-08-02 US disclosed