Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 10/20 | 0.54 |
| ▸ | APAF1 | O14727 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CASP3 | P42574 | 5/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 5/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 4/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.54 |
| ▸ | CASP6 | P55212 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP2 | O95551 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | CASP9 | P55211 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784203 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL6448568 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL29844316 | 0.75 | LOXL2 (0.61) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL1687342 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL1818129 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL824574 | 0.75 | KDM4E (1.00) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL150458 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL29488099 | 0.75 | KDM4E (1.00) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL1719778 | 0.75 | LOXL2 (0.61) | KDM4EGAALOXL2CDC25BAPAF1 | |
| SCHEMBL25911541 | 0.75 | KDM4E (0.60) | KDM4EGAALOXL2CDC25BAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116574056-A | Preparation method of fluoroisoquinolone compound | 五邑大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-108368053-A | Substituted benzazepine derivatives as antibacterial compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105859617-A | Fluoroisoquinolone compound and synthesis method thereof | 叶芳 | 2016-08-17 | — | — | CN | disclosed |
| CN-105859617-A | Fluoroisoquinolone compound and synthesis method thereof | 叶芳 | 2016-08-17 | — | — | CN | disclosed |
| WO-2007053352-A2 | PYRROLOQUINOLINONE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR2C | KDM4E 3529/4885GAA 3571/4885LOXL2 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.