Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 6/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | CCND3 | P30281 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311883 | 0.90 | TNIK (0.45) | DYRK2CDK6KDRCCND3CDK4 | |
| SCHEMBL5315552 | 0.87 | BDKRB1 (0.40) | DYRK2CDK6KDRCCND3CDK4 | |
| SCHEMBL5311867 | 0.80 | MERTK (0.45) | DYRK2CDK6CCND3CDK4CCNA2 | |
| SCHEMBL5333764 | 0.78 | TNIK (0.41) | KDR | |
| SCHEMBL5313507 | 0.78 | DYRK2 (0.45) | DYRK2CDK6LYNSRCKDR | |
| SCHEMBL5315261 | 0.78 | BDKRB1 (0.37) | DYRK2CDK6KDRCCND3CDK4 | |
| SCHEMBL5333804 | 0.77 | DRD4 (0.40) | KDR | |
| SCHEMBL5310432 | 0.76 | KDR (0.49) | KDRCDK2 | |
| SCHEMBL5312320 | 0.76 | KDR (0.49) | DYRK2KDR | |
| SCHEMBL5314922 | 0.73 | PDE1B (0.35) | DYRK2CDK6CCND3CDK4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |