Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 4/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311883 | 0.91 | TNIK (0.45) | CDK6CDK4CCND3KDRGRM2 | |
| SCHEMBL5315261 | 0.90 | BDKRB1 (0.37) | BDKRB1CCND1CDK6CDK4CCND3 | |
| SCHEMBL5310432 | 0.88 | KDR (0.49) | MCHR1HTR2CKDRGRM2 | |
| SCHEMBL5312754 | 0.87 | DYRK2 (0.49) | CDK6CDK4CCND3KDRDYRK2 | |
| SCHEMBL5311867 | 0.81 | MERTK (0.45) | CDK6CDK4CCND3BTKDYRK2 | |
| SCHEMBL5313507 | 0.80 | DYRK2 (0.45) | CCND1CDK6CDK4CCND3KDR | |
| SCHEMBL5312577 | 0.80 | KDR (0.49) | KDR | |
| SCHEMBL5333804 | 0.79 | DRD4 (0.40) | KDRTBK1 | |
| SCHEMBL5333764 | 0.79 | TNIK (0.41) | KDRGRM2TBK1 | |
| SCHEMBL5314023 | 0.79 | KDR (0.47) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |