Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313737 | 0.83 | HDAC1 (0.61) | HDAC1HDAC6KMT2AMAPTALDH1A1 | |
| SCHEMBL1256116 | 0.76 | L3MBTL1 (0.57) | ALDH1A1HPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL22042582 | 0.76 | RAB9A (0.57) | HDAC1HDAC6MAPTALDH1A1GAA | |
| SCHEMBL1876108 | 0.76 | POLB (0.47) | KITALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL5177505 | 0.75 | HDAC1 (0.50) | HDAC1HDAC6KMT2AMAPTALDH1A1 | |
| SCHEMBL5662698 | 0.73 | RAB9A (0.47) | HDAC1HDAC6KMT2AMAPTALDH1A1 | |
| SCHEMBL1017443 | 0.73 | HDAC1 (0.65) | HDAC1HDAC6KMT2AMAPTALDH1A1 | |
| SCHEMBL3923329 | 0.71 | FAAH (0.52) | KITALDH1A1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10901938 | 0.71 | KDM4E (0.66) | KMT2AMAPTALDH1A1GAAHPGD | |
| SCHEMBL1721447 | 0.69 | KIT (0.43) | KITKMT2AALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |