Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157466 | 0.81 | HSD11B1 (0.58) | HSD11B1HSD17B10L3MBTL1EPHX2EPHX1 | |
| SCHEMBL4779124 | 0.79 | ALDH1A1 (0.54) | L3MBTL1EPHX2KMT2AALDH1A1 | |
| SCHEMBL29117233 | 0.77 | ALDH1A1 (0.60) | HSD17B10L3MBTL1EPHX2KMT2AALDH1A1 | |
| SCHEMBL29117235 | 0.77 | ALDH1A1 (0.60) | HSD17B10L3MBTL1EPHX2KMT2AALDH1A1 | |
| SCHEMBL13602122 | 0.77 | HSD11B1 (0.74) | HSD11B1HSD17B10L3MBTL1EPHX2NPC1 | |
| SCHEMBL3920458 | 0.75 | HSD11B1 (0.69) | HSD11B1HSD17B10L3MBTL1EPHX2NPC1 | |
| SCHEMBL23210482 | 0.73 | ITGB3 (0.43) | ALDH1A1 | |
| SCHEMBL3461854 | 0.73 | ITGB3 (0.43) | ALDH1A1 | |
| SCHEMBL314947 | 0.73 | ITGB3 (0.43) | ALDH1A1 | |
| SCHEMBL15085132 | 0.73 | BCHE (0.50) | NPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057768-A2 | SULFONYL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |