Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311989 | 0.94 | LCK (0.37) | LCKCSNK1DMAPTGPR52IRAK4 | |
| SCHEMBL5314719 | 0.88 | ALDH1A1 (0.35) | LCKHPGDMAPTIRAK4KDR | |
| SCHEMBL5312890 | 0.88 | LCK (0.38) | LCKCSNK1DMAPTIRAK4KDR | |
| SCHEMBL5310797 | 0.86 | LCK (0.35) | LCKMAPTIRAK4KDRWNT3A | |
| SCHEMBL5311529 | 0.86 | LCK (0.39) | LCKMAPTIRAK4KDRKDM4E | |
| SCHEMBL14530871 | 0.86 | LCK (0.39) | LCKMAPTIRAK4KDRMEN1 | |
| SCHEMBL5312033 | 0.86 | LCK (0.36) | LCKIRAK4KDRKIT | |
| SCHEMBL5312732 | 0.85 | LCK (0.37) | LCKIRAK4KDRMEN1KMT2A | |
| SCHEMBL5312746 | 0.85 | LCK (0.37) | LCKMAPTIRAK4KDRKDM4E | |
| SCHEMBL5310041 | 0.85 | POLB (0.48) | LCKHPGDKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |