SCHEMBL5312830

SCHEMBL5312830

C=C(C)C(=O)O[Si](C)(C)CCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 3/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3475766 0.82 RECQL (0.32)
SCHEMBL27361285 0.78 TSHR (0.44) ALDH1A1TSHRTHRB
SCHEMBL29368937 0.77 FAAH (0.32)
SCHEMBL2308683 0.76 TSHR (0.42) ALDH1A1TSHRTHRB
SCHEMBL9578402 0.76 TSHR (0.35) ALDH1A1TSHRTHRB
SCHEMBL2404652 0.76 TSHR (0.42) ALDH1A1TSHRTHRB
SCHEMBL27428980 0.75 TSHR (0.41) ALDH1A1TSHRTHRB
SCHEMBL19499561 0.74 TSHR (0.34) ALDH1A1TSHRTHRB
SCHEMBL5838985 0.73 TSHR (0.48) ALDH1A1TSHRTHRB
SCHEMBL9578410 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1471069-B1 Preparation of silyl ketene acetals and disilyl ketene acetals SHINETSU CHEMICAL CO (JP) 2007-04-18 EP disclosed
EP-1471069-A1 Preparation of silyl ketene acetals and disilyl ketene acetals SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-10-27 EP disclosed