SCHEMBL531338

SCHEMBL531338

O=C1CC(c2ccccc2)CN1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
TSHR P16473 2/20 0.56
MTNR1A P48039 1/20 0.54
PDE4A P27815 4/20 0.51
ALDH1A1 P00352 3/20 0.51
PDE4B Q07343 2/20 0.51
PDE4C Q08493 2/20 0.51
PDE4D Q08499 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
PKM P14618 1/20 0.51
THRB P10828 1/20 0.51
GAA P10253 3/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3150368 1.00 MAPK1 (0.56) MAPK1TSHRMTNR1APDE4AALDH1A1
SCHEMBL3159001 1.00 MAPK1 (0.56) MAPK1TSHRMTNR1APDE4AALDH1A1
Hydrochloric Acid SCHEMBL29540251 0.98 MAPK1 (0.55) MAPK1TSHRMTNR1APDE4AALDH1A1
Trifluoroacetic Acid SCHEMBL29921233 0.87 MAPK1 (0.47) MAPK1TSHRMTNR1APDE4AALDH1A1
Acetic Acid Methyl Ester SCHEMBL28100313 0.85 PDE4A (0.51) MAPK1TSHRMTNR1APDE4AALDH1A1
SCHEMBL1568261 0.80 SLC18A3 (0.53) MAPK1MTNR1AGAAMAPTHPGD
SCHEMBL2790425 0.80 DDB1 (0.49) MAPK1MTNR1AGAAMAPTHPGD
SCHEMBL22831445 0.80 TSHR (0.57) MAPK1TSHRPDE4AALDH1A1PDE4B
SCHEMBL14544184 0.80 TSHR (0.61) MAPK1TSHRPDE4AALDH1A1PDE4B
SCHEMBL21590315 0.80 TSHR (0.53) MAPK1TSHRMTNR1APDE4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120943874-B Temperature-resistant oil displacement and drainage aid, preparation method and application thereof 盘锦汇明实业有限公司 2026-02-27 CN claimed
CN-112608267-B Synthetic method of 4-phenyl-2-pyrrolidone 赣州中能实业有限公司 2022-10-25 CN claimed
CN-112608267-A Synthetic method of 4-phenyl-2-pyrrolidone 南京艾斯特医药科技有限公司 2021-04-06 CN claimed
CN-108530333-B Preparation method of 4-phenyl-2-pyrrolidone 杭州卢普生物科技有限公司 2020-01-14 CN claimed
CN-106083685-B A kind of preparation method of phenyl Piracetam 东北制药集团股份有限公司 2019-08-23 CN claimed
CN-108530333-A A kind of preparation method of 4- phenyl -2-Pyrrolidone 杭州卢普生物科技有限公司 2018-09-14 CN claimed
CN-106083685-A A kind of preparation method of phenyl piracetam 东北制药集团股份有限公司 2016-11-09 CN claimed
CN-105647080-A Flexible electromagnetic-wave shielding material and preparation method thereof 苏州科茂电子材料科技有限公司 2016-06-08 CN claimed
CN-105175981-A Composite environmental-friendly flame retardant for POM YANTAI SHUNLONG CHEMICAL SCIENCE & TECHNOLOGY CO LTD 2015-12-23 CN claimed
CN-105153006-A Synthetic method for 4-phenyl-2-pyrrolidone CHANGZHOU QIANGDA BAOCHENG CHEMICAL ENGINEERING CO LTD 2015-12-16 CN claimed
US-9102615-B2 N-Carbamoylmethy1-4-(R)-phenyl-2-pyrrolidinone, method of its preparation and pharmaceutical use Joint Stock Company (JSC) “OLAINFARM” (LV) 2015-08-11 US claimed
US-20140315972-A1 RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide compound having modulatory activity with a commensurate effect, pharmaceutical substance (variants) and its application, composition (variants) thereof AKHAPKINA, VALENTINA IVANOVNA (RU) 2014-10-23 US claimed
EP-2762138-A1 PHARMACEUTICAL SUBSTANCE (VARIANTS) AND COMPOSITIONS BASED THEREON WHICH EXHIBIT MODULATORY ACTIVITY WITH A COMMENSURATE EFFECT Akhapkina, Valentina Ivanovna (RU) 2014-08-06 EP claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
EP-2013166-B1 N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE AKCIJU SABIEDRIBA OLAINFARM (LV) 2010-03-10 EP claimed
US-20100022784-A1 N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use Joint Stock Company "Olainfarm" (LV) 2010-01-28 US claimed
EP-0439766-A2 Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity ARZNEIMITTELWERK DRESDEN GmbH (DE) 1991-08-07 EP claimed
EP-0363489-A1 METHOD FOR OBTAINING 4-PHENYL-2-PYRROLIDONE-ACETIC-1 ACID AMIDE 2-i MOSKOVSKY GOSUDARSTVENNY MEDITSINSKY INSTITUT IMENI N.I. PIROGOVA (SU) 1990-04-18 EP claimed
US-12590078-B2 2026-03-31 US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022784-A1 N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use PRMT6, CPS1, JMJD6 MAPK1 4761/4885TSHR 1892/4885MTNR1A 1261/4885
US-12590078-B2 ADRM1, USP19, USP1 MAPK1 2366/4885TSHR 835/4885MTNR1A 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.