Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000702 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNATDP1MAPT | |
| SCHEMBL6662488 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAMAPTMAPK1 | |
| SCHEMBL351824 | 0.76 | TSHR (0.48) | ALDH1A1TSHRLMNATDP1MAPT | |
| SCHEMBL30945319 | 0.76 | TSHR (0.48) | ALDH1A1TSHRLMNATDP1MAPT | |
| SCHEMBL5313485 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNATDP1MAPT | |
| SCHEMBL2227750 | 0.75 | TSHR (0.48) | ALDH1A1TSHRLMNATDP1MAPT | |
| SCHEMBL4339044 | 0.75 | PTPRC (0.41) | ALDH1A1TSHRLMNAMAPTKMT2A | |
| SCHEMBL6752686 | 0.73 | OPRM1 (0.42) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL6659536 | 0.72 | CHRNB2 (0.49) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL345760 | 0.72 | HSD17B10 (0.48) | ALDH1A1TSHRLMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006316-B2 | 9H-pyrrolo-dipyridine derivatives | UCB Biopharma SRL (BE) | 2024-06-11 | — | — | US | disclosed |
| US-20220213103-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2022-07-07 | — | — | US | disclosed |
| US-11312716-B2 | 9H-pyrrolo-dipyridine derivatives | UCB Biopharma SRL | 2022-04-26 | — | — | US | disclosed |
| EP-3253762-B1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-05-05 | — | — | EP | disclosed |
| US-20210047326-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2021-02-18 | — | — | US | disclosed |
| CN-107207508-B | 9H-pyrrolo-bipyridine derivatives | UCB生物制药私人有限公司 | 2020-02-28 | — | — | CN | disclosed |
| US-20180022748-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022748-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2018-01-25 | — | — | US | disclosed |
| CN-107207508-A | 9H-pyrrolo-bipyridine derivatives | UCB生物制药私人有限公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2016124508-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-11 | — | — | WO | disclosed |
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| EP-0637300-B1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMA (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0637300-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993020055-A1 | ANTIPROLIFERATIVE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213103-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | MAPT, PSEN1, PRNP | ALDH1A1 3567/4885TSHR 3778/4885LMNA 1731/4885 |
| US-20210047326-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | MAPT, PSEN1, PRNP | ALDH1A1 3567/4885TSHR 3778/4885LMNA 1731/4885 |
| US-12006316-B2 | 9H-pyrrolo-dipyridine derivatives | MAPT, PSEN1, PRNP | ALDH1A1 3567/4885TSHR 3778/4885LMNA 1731/4885 |
| US-11312716-B2 | 9H-pyrrolo-dipyridine derivatives | MAPT, PSEN1, PRNP | ALDH1A1 3567/4885TSHR 3778/4885LMNA 1731/4885 |
| US-20180022748-A1 | 9H-PYRROLO-DIPYRIDINE DERIVATIVES | MAPT, PSEN1, PRNP | ALDH1A1 3567/4885TSHR 3778/4885LMNA 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.