Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323934 | 0.78 | CA12 (0.43) | MAPTMEN1KMT2AGAAALDH1A1 | |
| Biphenyl SCHEMBL27762344 | 0.72 | MAPK1 (0.49) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4970947 | 0.62 | HTR7 (0.44) | MAPTMEN1KMT2ANPC1RAB9A | |
| Piperazine SCHEMBL28533863 | 0.60 | ADRB1 (0.58) | MAPTL3MBTL1GAAALDH1A1MCL1 | |
| SCHEMBL5560748 | 0.60 | AXL (0.59) | MAPTMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5980911 | 0.59 | HSD17B10 (0.48) | MAPTALDH1A1RECQLRAB9ACA12 | |
| SCHEMBL9122080 | 0.59 | APP (0.50) | MAPTL3MBTL1GAAALDH1A1MCL1 | |
| SCHEMBL28198 | 0.59 | CA1 (0.67) | MAPTGAAALDH1A1POLBRECQL | |
| SCHEMBL6423919 | 0.59 | CA1 (0.67) | MAPTGAAALDH1A1POLBRECQL | |
| SCHEMBL4789631 | 0.58 | HTR2C (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |