Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050175 | 0.84 | GABRA1 (0.39) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL677316 | 0.83 | CYP19A1 (0.46) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL2910464 | 0.82 | KDM4E (0.42) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL7048608 | 0.80 | PTGS2 (0.47) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL29818735 | 0.79 | ERN1 (0.46) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL2218270 | 0.78 | PTGS2 (0.43) | ACHEGABRA1GABRB2CYP3A4MAPT | |
| SCHEMBL27975315 | 0.77 | ERN1 (0.41) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL11464793 | 0.77 | PKM (0.58) | ERN1ALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL2911255 | 0.76 | ALDH1A1 (0.58) | ERN1ALDH1A1KDM4ETDP1PRKDC | |
| SCHEMBL5657695 | 0.76 | KDM4E (0.61) | ERN1ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114173750-A | Improving the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2007053915-A2 | NARINGENIN DERIVATIVES WITH SELECTIVITY ON ERS | UNIVERSITEIT GENT (BE) | 2007-05-18 | — | — | WO | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4404277-A | CYANINE DYES, SILVER HALIDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-13 | — | — | US | disclosed |