SCHEMBL5314142

SCHEMBL5314142

O=S(=O)(O)c1cccnc1-c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 2/20 0.50
HIF1A Q16665 2/20 0.50
P4HTM Q9NXG6 2/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
DOHH Q9BU89 1/20 0.50
ALOX15 P16050 3/20 0.44
TP53 P04637 3/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640294 0.90 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8641370 0.87 TDP2 (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4660499 0.85 COMT (0.50) KDM4ELMNACYP1A2HIF1APOLB
SCHEMBL4660500 0.83 KDM4E (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8641367 0.83 KDM4E (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8514484 0.82 CA2 (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8743462 0.81 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL27903420 0.80 KDM4E (0.70) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5850523 0.80 PTGS1 (0.47) KDM4ELMNACYP1A2HIF1AP4HTM
SCHEMBL5010922 0.80 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109154614-B Compositions, devices and methods for cell separation 四方控股公司 2022-01-28 CN claimed
CN-110891969-A Methods and compositions for modulating immune cells 四方控股公司 2020-03-17 CN claimed
US-20050123937-A1 Methods for the electrochemical detection of target compounds UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE 2005-06-09 US claimed
WO-2004092708-A2 METHODS FOR THE ELECTROCHEMICAL DETECTION OF TARGET COMPOUNDS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2004-10-28 WO claimed
EP-0588225-B1 Process for the preparation of aldehydes BASF AG (DE) 1997-06-18 EP claimed
US-5387719-A Preparation of aldehydes BASF AKTIENGESELLSCHAFT (DE) 1995-02-07 US claimed
EP-0588225-A2 Process for the preparation of aldehydes BASF Aktiengesellschaft (DE) 1994-03-23 EP claimed
CN-109154614-B Compositions, devices and methods for cell separation 四方控股公司 2022-01-28 CN disclosed
CN-110891969-A Methods and compositions for modulating immune cells 四方控股公司 2020-03-17 CN disclosed
CN-101810613-A The method and composition of control ectoparasite HATCH TECH HOLDINGS CO LTD 2010-08-25 CN disclosed
CN-101686678-A compositions and methods for controlling infestation HATCHTECH PTY LTD 2010-03-31 CN disclosed
CN-100593419-C Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD 2010-03-10 CN disclosed
CN-101132696-A Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD (AU) 2008-02-27 CN disclosed
WO-2007048943-A1 HETEROGENEOUS CATALYST SYSTEM AND THE USE THEREOF NOVALYST DISCOVERY (FR) 2007-05-03 WO disclosed
CN-1822854-A Methods and compositions for controlling ectoparasites HATCHTECH PTY LTD (AU) 2006-08-23 CN disclosed
EP-0750602-B1 PROCESS FOR PRODUCING ALCOHOLS AND/OR ALDEHYDES BASF AG (DE) 1998-08-19 EP disclosed
EP-0588225-B1 Process for the preparation of aldehydes BASF AG (DE) 1997-06-18 EP disclosed
EP-0588225-A2 Process for the preparation of aldehydes BASF Aktiengesellschaft (DE) 1994-03-23 EP disclosed