SCHEMBL5850523

SCHEMBL5850523

O=S(=O)(O)c1cccnc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
COMT P21964 1/20 0.44
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
ALOX15 P16050 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
SLC22A12 Q96S37 1/20 0.41
PTPRC P08575 2/20 0.40
CTSL P07711 1/20 0.40
CTSS P25774 1/20 0.40
PTPN13 Q12923 1/20 0.40
NSD2 O96028 2/20 0.39
MEN1 O00255 2/20 0.39
BLM P54132 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP2 O95551 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660499 0.86 COMT (0.50) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL28672150 0.84 ALDH1A1 (0.49) PTGS1PTGS2COMTALDH1A1CYP1A2
SCHEMBL5700053 0.81 PTGS2 (0.59) PTGS1PTGS2ALDH1A1TDP1SLC22A12
SCHEMBL784140 0.81 CA1 (0.51) PTGS1PTGS2ALDH1A1TDP1KDM4E
SCHEMBL8036594 0.80 MAPT (0.43) SMN1; SMN2
SCHEMBL5314142 0.80 KDM4E (0.50) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL20569781 0.79 PTGS2 (0.39) PTGS1PTGS2COMTALDH1A1SLC22A12
SCHEMBL5698942 0.78 TTR (0.47) PTGS1PTGS2COMTALDH1A1CYP1A2
SCHEMBL29233670 0.77 PTGS1 (0.44) PTGS1PTGS2ALDH1A1HSD17B10TDP1
SCHEMBL27727296 0.76 PTGS1 (0.45) PTGS1PTGS2ALDH1A1SLC22A12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026266-B2 Catalytic formulation and its preparation COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-04-11 US disclosed
CN-1538876-A Novel catalytic formulation and its preparation method 科学与工业研究委员会 2004-10-20 CN disclosed
US-20030092565-A1 Liquid-insoluble heterogeneous catalyst comprising a solid support and a deposit of active organometallic compound modified to include negatively charged groups and a Group 2A metal salt; heterogeous; easy separation COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-05-15 US disclosed
WO-2002078842-A1 A NOVEL CATALYTIC FORMULATION AND ITS PREPARATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-10-10 WO disclosed