SCHEMBL5314475

SCHEMBL5314475

Cc1ccc(SC2CCCCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.58
MAOB P27338 4/20 0.58
PTGIR P43119 1/20 0.44
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
CYP3A4 P08684 2/20 0.40
KMT2A Q03164 1/20 0.39
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
EPHX1 P07099 1/20 0.36
AR P10275 1/20 0.36
MAPT P10636 2/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15270961 1.00 MAOA (0.58) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL28758298 1.00 MAOA (0.58) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL28758302 1.00 MAOA (0.58) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL8361627 0.98 MAOA (0.55) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL24162601 0.94 MAOA (0.53) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL15271173 0.93 MAOA (0.50) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL11439138 0.89 CRBN (0.47) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL23295277 0.86 MAOA (0.65) MAOAMAOBPTGIRDDB1CRBN
SCHEMBL19223862 0.81 CRBN (0.42) MAOAMAOBDDB1CRBNNPC1
SCHEMBL2297073 0.79 CRBN (0.45) MAOAMAOBPTGIRDDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591207-B Synthesis method of cycloalkyl aryl thioether compound 台州学院 2024-03-26 CN disclosed
WO-2023095561-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR株式会社 2023-06-01 WO disclosed
CN-114591207-A Synthetic method of naphthenic base aryl thioether compound 台州学院 2022-06-07 CN disclosed
US-20220169580-A1 METHODS OF CARBON-CARBON BOND FRAGMENTATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-06-02 US disclosed
EP-3592729-B1 CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2021-06-30 EP disclosed
US-20210130286-A1 CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2021-05-06 US disclosed
US-20210130286-A1 CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2021-05-06 US disclosed
US-9650456-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-05-16 US disclosed
CN-104220466-B For the method preparing polydiene 株式会社普利司通 2016-09-21 CN disclosed
EP-2825574-B1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORP (JP) 2016-02-24 EP disclosed
US-20150031845-A1 Process For Producing Polydienes BRIDGESTONE CORPORATION (JP) 2015-01-29 US disclosed
EP-2825574-A1 PROCESS FOR PRODUCING POLYDIENES Bridgestone Corporation (JP) 2015-01-21 EP disclosed
CN-104220466-A Process for producing polydienes BRIDGESTSONE CORP 2014-12-17 CN disclosed
WO-2013138270-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTSONE CORPORATION (JP) 2013-09-19 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2003007954-A2 SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220169580-A1 METHODS OF CARBON-CARBON BOND FRAGMENTATION CYCS, COX6C, COXFA4L2 MAOA 3388/4885MAOB 1483/4885PTGIR 4608/4885
US-20210130286-A1 CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION AOX1, TYR, CXXC4 MAOA 38/4885MAOB 35/4885PTGIR 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.