Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965952 | 0.76 | PGR (0.57) | MEN1KMT2AL3MBTL1MMP3ALDH1A1 | |
| SCHEMBL531388 | 0.76 | KMT2A (0.49) | MEN1KMT2AALDH1A1ATMPOLB | |
| SCHEMBL532486 | 0.76 | KMT2A (0.49) | MEN1KMT2AALDH1A1ATMPOLB | |
| SCHEMBL13562544 | 0.74 | PLA2G4A (0.56) | PLA2G4ACES1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19349131 | 0.74 | MEN1 (0.61) | MEN1KMT2AL3MBTL1MMP3ALDH1A1 | |
| SCHEMBL531314 | 0.73 | KDM4C (0.46) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL15812249 | 0.73 | KMT2A (0.59) | MEN1KMT2AL3MBTL1MMP3ALDH1A1 | |
| SCHEMBL15670744 | 0.73 | KMT2A (0.59) | MEN1KMT2AL3MBTL1MMP3ALDH1A1 | |
| SCHEMBL13562697 | 0.72 | PLA2G4A (0.60) | PLA2G4ACES1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15676363 | 0.72 | ADAM17 (0.41) | MEN1KMT2AL3MBTL1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |