Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531472 | 0.73 | MEN1 (0.45) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL17965952 | 0.73 | PGR (0.57) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL531388 | 0.73 | KMT2A (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL532486 | 0.73 | KMT2A (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL531457 | 0.73 | PLA2G4A (0.48) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL27983616 | 0.71 | KDM4C (0.45) | KDM4C | |
| SCHEMBL8087046 | 0.71 | KDM4C (0.54) | KDM4CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19349131 | 0.71 | MEN1 (0.61) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL1197307 | 0.71 | L3MBTL1 (0.51) | KDM4CALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL3202566 | 0.70 | GSK3B (0.49) | ALDH1A1MAPTL3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |