Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160284 | 0.89 | TRPA1 (0.39) | TRPA1CYP1A2MAPTLMNATSHR | |
| SCHEMBL5318426 | 0.88 | TRPA1 (0.34) | TRPA1CYP1A2RAB9ANPC1PKM | |
| SCHEMBL5312106 | 0.87 | TRPA1 (0.35) | TRPA1CYP1A2MAPTLMNARAB9A | |
| SCHEMBL5314313 | 0.86 | TRPA1 (0.34) | TRPA1CYP1A2MAPTLMNATSHR | |
| SCHEMBL5314730 | 0.86 | KMT2A (0.36) | TRPA1CYP1A2RAB9ANPC1ATM | |
| SCHEMBL5316923 | 0.85 | TRPA1 (0.36) | TRPA1CYP1A2MAPTRAB9ANPC1 | |
| SCHEMBL4158996 | 0.84 | TRPA1 (0.34) | TRPA1CYP1A2MAPTLMNATSHR | |
| SCHEMBL5389734 | 0.81 | TLR7 (0.39) | MAPTLMNAMAPK1RAB9ANPC1 | |
| SCHEMBL5314713 | 0.79 | TRPA1 (0.34) | TRPA1CYP1A2MAPTRAB9ANPC1 | |
| SCHEMBL5314173 | 0.78 | KDM4E (0.35) | LMNAMAPK1RAB9ANPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |