Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312106 | 0.91 | TRPA1 (0.35) | KMT2AMEN1TRPA1RAB9ARXFP1 | |
| SCHEMBL5314313 | 0.89 | TRPA1 (0.34) | KMT2AMEN1TRPA1RAB9ACYP1A2 | |
| SCHEMBL4160284 | 0.88 | TRPA1 (0.39) | KMT2AMEN1TRPA1RAB9ARXFP1 | |
| SCHEMBL5318426 | 0.86 | TRPA1 (0.34) | TRPA1RAB9ACYP1A2NPC1ATM | |
| SCHEMBL5314653 | 0.86 | TRPA1 (0.36) | KMT2AMEN1TRPA1RAB9ARXFP1 | |
| SCHEMBL5316923 | 0.85 | TRPA1 (0.36) | KMT2AMEN1TRPA1RAB9ARXFP1 | |
| SCHEMBL5389734 | 0.85 | TLR7 (0.39) | RAB9APOLBNPC1 | |
| SCHEMBL5312164 | 0.83 | TRPA1 (0.33) | KMT2ATRPA1RAB9ACYP1A2POLB | |
| SCHEMBL5314713 | 0.83 | TRPA1 (0.34) | KMT2AMEN1TRPA1RAB9ACYP1A2 | |
| SCHEMBL5314883 | 0.83 | MEN1 (0.33) | KMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |