SCHEMBL5314740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5313590	0.97	KIF11 (0.38)	KIF11GUCY1A1GUCY1B1VDRAR
	SCHEMBL5314416	0.90	KIF11 (0.39)	KIF11VDRARSLC1A3SLC1A2
	SCHEMBL5314794	0.89	KIF11 (0.38)	KIF11VDRARSLC1A3SLC1A2
	SCHEMBL21369747	0.84	SMN1; SMN2 (0.46)	GUCY1A1GUCY1B1HTTMAPTALDH1A1
	SCHEMBL9852005	0.81	MAPT (0.58)	HTTMAPTALDH1A1POLBHPGD
	SCHEMBL574466	0.79	ALDH1A1 (0.33)	GUCY1A1GUCY1B1MAPTALDH1A1
	SCHEMBL18747679	0.78	SMN1; SMN2 (0.49)	HTTMAPTALDH1A1SMN1; SMN2PKM
	SCHEMBL2743946	0.77	CYP3A4 (0.54)	GUCY1A1GUCY1B1MAPTALDH1A1PKM
	SCHEMBL5314795	0.76	MET (0.41)	KIF11VDRARSLC1A3SLC1A2
	SCHEMBL24276947	0.76	ALDH1A1 (0.41)	GUCY1A1GUCY1B1HTTMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.