Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | NPC1 | O15118 | 1/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | CRHBP | P24387 | 1/20 | 0.81 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.81 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.76 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192588 | 0.91 | HCAR3 (0.77) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL1306790 | 0.89 | MAPT (0.65) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL2248076 | 0.89 | HCAR3 (0.74) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL1306733 | 0.88 | MAPT (0.64) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL2246295 | 0.88 | MAPT (0.64) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL2252228 | 0.88 | MAPT (0.82) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL20797593 | 0.87 | MAPT (0.73) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL3720388 | 0.87 | MAPT (0.74) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL2688335 | 0.86 | HCAR3 (1.00) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL9725412 | 0.86 | ALDH1A1 (0.63) | MAPTALDH1A1RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |