Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514221 | 0.84 | XDH (0.57) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL832227 | 0.81 | RAB9A (0.67) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7493127 | 0.80 | FLT3 (0.57) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4666737 | 0.80 | F7 (0.60) | RAB9ANPC1HRH3PDGFRBFLT3 | |
| SCHEMBL3494717 | 0.80 | HRH4 (0.51) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29496122 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL318243 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23486667 | 0.78 | MMP13 (0.51) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL829726 | 0.78 | HRH4 (0.55) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5795136 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574994-A | A kind of anti-tumor drug and its preparation method and application | 熊磊 | 2019-04-05 | — | — | CN | claimed |
| CN-109574994-A | A kind of anti-tumor drug and its preparation method and application | 熊磊 | 2019-04-05 | — | — | CN | disclosed |
| WO-2007065032-A2 | COMPOUNDS AND METHODS FOR INHIBITING VIRAL ENTRY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2006034480-A2 | SULFONAMIDE BICYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |