Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839021 | 0.89 | FFAR4 (0.58) | BCHESMN1; SMN2KDM4EKMT2ASLC2A1 | |
| SCHEMBL6136228 | 0.87 | HDAC3 (0.58) | SMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL16839011 | 0.87 | CD274 (0.52) | BCHELMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL5881099 | 0.85 | APP (0.73) | BCHEAPPNPC1RAB9APKM | |
| SCHEMBL5113589 | 0.84 | BCHE (0.69) | BCHENPC1RAB9APKMLMNA | |
| SCHEMBL6136380 | 0.84 | L3MBTL1 (0.61) | BCHELMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL9724394 | 0.83 | APP (0.62) | APPNPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL25292445 | 0.83 | SLC2A1 (0.52) | BCHELMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL6136444 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4949263 | 0.82 | BCHE (0.77) | BCHENPC1RAB9APKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |