Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 4/20 | 0.30 |
| ▸ | MITF | O75030 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316827 | 0.81 | KDM4E (0.33) | KMT2AMEN1KDM4EMAPTTDP1 | |
| SCHEMBL5315450 | 0.72 | ALDH1A1 (0.35) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4088358 | 0.67 | KMT2A (0.45) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1426816 | 0.65 | KMT2A (0.46) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL20861812 | 0.64 | CYP3A4 (0.46) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| Bromide SCHEMBL1457139 | 0.64 | KMT2A (0.45) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6428552 | 0.59 | PARP1 (0.48) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL31219282 | 0.59 | PARP1 (0.48) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14128779 | 0.58 | CYP3A4 (0.56) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL3399748 | 0.58 | KMT2A (0.40) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838279-A1 | AGENTS FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-10-03 | — | — | EP | claimed |
| WO-2006077039-A1 | AGENTS FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-07-27 | — | — | WO | claimed |