Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426816 | 0.90 | KMT2A (0.46) | KMT2AKDM4EHPGDMEN1SMN1; SMN2 | |
| Bromide SCHEMBL1457139 | 0.88 | KMT2A (0.45) | KMT2AKDM4EHPGDMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4088358 | 0.88 | KMT2A (0.45) | KMT2AKDM4EHPGDMEN1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL3400219 | 0.80 | HSD17B10 (0.41) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL1457606 | 0.74 | — | — | |
| SCHEMBL1426641 | 0.69 | HSD17B10 (0.47) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3118058 | 0.69 | ALDH1A1 (0.36) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4605053 | 0.68 | HSD17B10 (0.46) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1830280 | 0.68 | KDM4E (0.31) | KMT2AKDM4EHPGDMEN1 | |
| SCHEMBL3118165 | 0.67 | MAPT (0.50) | KMT2AKDM4EHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044977-B1 | Hair dye with oxidative pre-treatment | HENKEL AG & CO KGAA (DE) | 2018-02-14 | — | — | EP | disclosed |
| EP-1944010-B1 | Brightening and/or colouring agent with acrylic acid derivative(s) | HENKEL AG & CO KGAA (DE) | 2015-03-11 | — | — | EP | disclosed |
| EP-2200735-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COLORING AGENTS FOR KERATINIC FIBERS | Henkel AG & Co. KGaA (DE) | 2010-06-30 | — | — | EP | disclosed |
| EP-2196184-A1 | Hair dye with colour indicator | Henkel AG & Co. KGaA (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2081543-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | Henkel AG & Co. KGaA (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2009053127-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COLORING AGENTS FOR KERATINIC FIBERS | HENKEL AG & CO. KGAA (DE) | 2009-04-30 | — | — | WO | disclosed |
| EP-2044977-A2 | Hair dye with oxidative pre-treatment | Henkel AG & Co. KGaA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1972323-A2 | Hair colorant | Henkel AG & Co. KGaA (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2008095558-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | HENKEL AG & CO. KGAA (DE) | 2008-08-14 | — | — | WO | disclosed |
| EP-1944010-A2 | Brightening and/or colouring agent with acrylic acid derivative(s) | Henkel AG & Co. KGaA (DE) | 2008-07-16 | — | — | EP | disclosed |