Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314828 | 0.89 | MCHR1 (0.37) | ALDH1A1MCHR1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5314377 | 0.89 | MCHR1 (0.33) | HPGDMCHR1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5314131 | 0.86 | TSHR (0.34) | ALDH1A1MCHR1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5311672 | 0.86 | PTPRZ1 (0.32) | MCHR1PTPRZ1EPHX2NR1H4PDE2A | |
| SCHEMBL5315475 | 0.85 | MCHR1 (0.35) | ALDH1A1HPGDMCHR1PTPRZ1EPHX2 | |
| SCHEMBL5314000 | 0.85 | MTNR1A (0.40) | ALDH1A1POLBHPGDGAAKMT2A | |
| SCHEMBL5313318 | 0.84 | MAPT (0.42) | ALDH1A1HPGDPTPRZ1EPHX2NR1H4 | |
| SCHEMBL5312106 | 0.80 | TRPA1 (0.35) | POLBMCHR1PDE2AKCNK2KCNK10 | |
| SCHEMBL13774526 | 0.78 | MCHR1 (0.37) | ALDH1A1HPGDMCHR1PTPRZ1EPHX2 | |
| SCHEMBL5314173 | 0.78 | KDM4E (0.35) | ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |