Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 4/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315841 | 0.89 | ALDH1A1 (0.37) | MCHR1ALDH1A1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5314377 | 0.88 | MCHR1 (0.33) | MCHR1SMN1; SMN2PTPRZ1EPHX2NR1H4 | |
| SCHEMBL5315475 | 0.85 | MCHR1 (0.35) | MCHR1ALDH1A1PTPRZ1EPHX2NR1H4 | |
| SCHEMBL4149965 | 0.85 | ACKR3 (0.38) | MCHR1ACKR3ALDH1A1SMN1; SMN2PTPRZ1 | |
| SCHEMBL5314131 | 0.85 | TSHR (0.34) | MCHR1ALDH1A1PTPRZ1HTTEPHX2 | |
| SCHEMBL5311672 | 0.84 | PTPRZ1 (0.32) | MCHR1PTPRZ1EPHX2NR1H4KCNK2 | |
| SCHEMBL5314000 | 0.83 | MTNR1A (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5313318 | 0.82 | MAPT (0.42) | ALDH1A1SMN1; SMN2PTPRZ1HTTEPHX2 | |
| SCHEMBL5312106 | 0.78 | TRPA1 (0.35) | MCHR1KCNK2KCNK10 | |
| SCHEMBL13774526 | 0.78 | MCHR1 (0.37) | MCHR1ALDH1A1SMN1; SMN2PTPRZ1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |