Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.30 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314828 | 0.85 | MCHR1 (0.37) | MCHR1PTPRZ1ALDH1A1EPHX2NR1H4 | |
| SCHEMBL5315841 | 0.85 | ALDH1A1 (0.37) | MCHR1GAAHPGDHSD17B10PTPRZ1 | |
| SCHEMBL5314131 | 0.85 | TSHR (0.34) | MCHR1PTPRZ1ALDH1A1EPHX2NR1H4 | |
| SCHEMBL5311672 | 0.84 | PTPRZ1 (0.32) | MCHR1PTPRZ1EPHX2NR1H4KCNK2 | |
| SCHEMBL4146959 | 0.84 | L3MBTL1 (0.35) | MCHR1L3MBTL1HPGDHSD17B10PTPRZ1 | |
| SCHEMBL5314377 | 0.83 | MCHR1 (0.33) | MCHR1L3MBTL1HPGDPTPRZ1EPHX2 | |
| SCHEMBL5313318 | 0.82 | MAPT (0.42) | L3MBTL1HPGDPTPRZ1ALDH1A1EPHX2 | |
| SCHEMBL5314000 | 0.79 | MTNR1A (0.40) | GAAL3MBTL1HPGDALDH1A1 | |
| SCHEMBL5312106 | 0.78 | TRPA1 (0.35) | MCHR1KCNK2KCNK10 | |
| SCHEMBL5314123 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |