Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191341 | 0.78 | ADH1B (0.34) | ADH1BADH1CADH1AADH7LMNA | |
| SCHEMBL16606312 | 0.78 | CYP1A2 (0.52) | VNN1CYP1A2CYP2D6CYP2C9NAMPT | |
| SCHEMBL348709 | 0.75 | CYP1A2 (0.68) | ADH1BADH1CADH1AADH7CYP1A2 | |
| SCHEMBL2782804 | 0.74 | ADH1B (0.42) | ADH1BADH1CADH1AADH7HCAR2 | |
| SCHEMBL1302895 | 0.73 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL8763196 | 0.72 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL10651306 | 0.70 | — | — | |
| SCHEMBL2258462 | 0.70 | ALDH1A1 (0.40) | VNN1CYP1A2CYP2D6LMNA | |
| SCHEMBL347549 | 0.70 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL20185852 | 0.70 | VNN1 (0.53) | VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104442-A2 | PROCESS FOR THE MANUFACTURE OF A PRECURSOR OF VITAMIN B1 | DSM IP ASSETS B.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007058990-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0001760-B1 | ALPHA-AMINOMETHYLENE-BETA-FORMYLAMINOPROPIONITRILE, PROCESS FOR ITS PREPARATION AND ITS USE IN THE PREPARATION OF 2-METHYL-4-AMINO-5-FORMYLAMINOMETHYLPYRIMIDINE | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |