Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315543 | 0.79 | CYP19A1 (0.49) | — | |
| SCHEMBL14919007 | 0.76 | LMNA (0.50) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3910175 | 0.71 | ADRB2 (0.42) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL26123689 | 0.71 | LMNA (0.51) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL15953934 | 0.70 | HSD17B10 (0.53) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL1871973 | 0.70 | HSD17B10 (0.53) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3908793 | 0.70 | KMT2A (0.41) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3914954 | 0.68 | ALDH1A1 (0.40) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5312198 | 0.68 | CYP1A2 (0.43) | CYP1A2SMN1; SMN2POLBMAPTALDH1A1 | |
| Methyl Isonicotinate SCHEMBL180574 | 0.67 | CYP1A2 (0.60) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840158-A1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |