Sugi Predict

Sugi Predict / Compounds / SCHEMBL531632

SCHEMBL531632

SCHEMBL531632

O=Cc1ccc([N+](=O)[O-])c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH5A1 P51649 1/20 0.73
▸ ABAT P80404 1/20 0.73
▸ XDH P47989 1/20 0.62
▸ ALDH1A1 P00352 4/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ LMNA P02545 1/20 0.61
▸ CYP1A2 P05177 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ CYP3A4 P08684 1/20 0.61
▸ CYP2C9 P11712 1/20 0.61
▸ HPGD P15428 1/20 0.61
▸ RECQL P46063 1/20 0.61
▸ BLM P54132 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.61
▸ TDP1 Q9NUW8 1/20 0.61
▸ GPR35 Q9HC97 1/20 0.58
▸ VCAM1 P19320 1/20 0.58
▸ TTR P02766 1/20 0.57
▸ PTGS2 P35354 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29687930 1.00 ALDH5A1 (0.73) ALDH5A1ABATXDHALDH1A1KDM4E
SCHEMBL7442127 0.86 ALDH5A1 (0.56) ALDH5A1ABATXDHALDH1A1KDM4E
SCHEMBL244093 0.85 ALDH5A1 (1.00) ALDH5A1ABATXDHALDH1A1KDM4E
Cyclohexylamine SCHEMBL7801795 0.84 ALDH5A1 (0.54) ALDH5A1ABATXDHALDH1A1KDM4E
SCHEMBL13981566 0.83 MAPT (0.59) ALDH5A1ABATXDHALDH1A1KDM4E
SCHEMBL31484716 0.82 ALDH5A1 (0.69) ALDH5A1ABATXDHALDH1A1MAPT
SCHEMBL1466944 0.82 ALDH5A1 (0.69) ALDH5A1ABATXDHALDH1A1MAPT
SCHEMBL8701746 0.81 ALDH5A1 (0.65) ALDH5A1ABATXDHALDH1A1KDM4E
Iodomethane SCHEMBL27504663 0.80 ALDH5A1 (0.90) ALDH5A1ABATXDHALDH1A1KDM4E
SCHEMBL5170549 0.80 MAPT (0.65) ALDH5A1ABATXDHALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1059 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383912-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&TECH INC. (KR) 2024-11-21 — — US claimed
EP-4414367-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&Tech Inc. (KR) 2024-08-14 — — EP claimed
CN-118076611-A New method for synthesizing decursin derivatives PRG科技株式会社 2024-05-24 — — CN claimed
CN-117820256-A Preparation method of near-infrared ratio type lysosome targeted carbon monoxide fluorescent probe and imaging application of near-infrared ratio type lysosome targeted carbon monoxide fluorescent probe in cells or living bodies 新乡医学院 2024-04-05 — — CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 — — US claimed
CN-115819242-B Preparation method of 3-hydroxy-4-nitrobenzaldehyde 台州学院 2023-12-05 — — CN claimed
CN-115340542-B Fluorescent probe for detecting phosgene and preparation method and use method thereof 浙江理工大学 2023-10-03 — — CN claimed
WO-2023058875-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE (주)피알지에스앤텍 2023-04-13 — — WO claimed
WO-2023040100-A1 METHOD FOR PREPARING 3-HYDROXY-4-NITROBENZALDEHYDE 台州学院 2023-03-23 — — WO claimed
CN-115819242-A Preparation method of 3-hydroxy-4-nitrobenzaldehyde 台州学院 2023-03-21 — — CN claimed
WO-2004022016-A1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-18 — — WO claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 — — US claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 — — WO claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 — — WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 — — WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 — — EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 — — EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 — — US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 — — US claimed
WO-2000038634-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383912-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRTN3, PARG, PLA2G12B ALDH5A1 3927/4885ABAT 2938/4885XDH 147/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ALDH5A1 52/4885ABAT 264/4885XDH 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.