Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.53 |
| ▸ | CBR1 | P16152 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317845 | 0.84 | AR (0.44) | KDM4EALDH1A1SMN1; SMN2MPOTPO | |
| SCHEMBL5317344 | 0.84 | KCNQ3 (0.42) | TTRMAPTHPGDNR1I2LMNA | |
| Soneclosan SCHEMBL29359126 | 0.81 | TTR (0.66) | TTRMAPTHPGDNR1I2LMNA | |
| Soneclosan SCHEMBL465591 | 0.81 | TTR (0.66) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL5316194 | 0.79 | SLC6A2 (0.47) | TTRMAPTSLC6A2SLC6A3MEN1 | |
| SCHEMBL10540653 | 0.76 | TTR (0.83) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL4586762 | 0.75 | TTR (0.63) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL11551188 | 0.75 | LTA4H (0.50) | — | |
| SCHEMBL14465585 | 0.75 | TTR (0.58) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL13778174 | 0.75 | TTR (0.58) | TTRMAPTHPGDNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |