Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | EPX | P11678 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316441 | 0.84 | TTR (0.53) | MPOTPOEPXLPOKDM4E | |
| SCHEMBL5317344 | 0.82 | KCNQ3 (0.42) | MPOTPOEPXLPOHTR2A | |
| SCHEMBL5318993 | 0.82 | ACHE (0.50) | ARMPOTPOEPXLPO | |
| SCHEMBL12386586 | 0.79 | AR (0.49) | ARHTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL16309243 | 0.78 | AR (0.54) | ARALDH1A1 | |
| SCHEMBL17930598 | 0.77 | NPSR1 (0.49) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10292484 | 0.74 | TRPA1 (0.56) | ARKDM4EALDH1A1GAA | |
| SCHEMBL5318389 | 0.74 | ALDH1A1 (0.53) | ARKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5320413 | 0.74 | MEN1 (0.41) | ARHTR2ASLC6A4KCNH2ALDH1A1 | |
| SCHEMBL5319900 | 0.73 | RAF1 (0.39) | ARALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | claimed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |