Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 6/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | EPX | P11678 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316441 | 0.84 | TTR (0.53) | PNLIPMPOTPOEPXLPO | |
| SCHEMBL5317845 | 0.82 | AR (0.44) | MPOTPOEPXLPOHTR2A | |
| SCHEMBL3650668 | 0.77 | MEN1 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL11547858 | 0.74 | KCNQ3 (0.48) | KCNQ3KCNQ2KCNE1KCNQ1MPO | |
| SCHEMBL1956720 | 0.74 | FFAR4 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5316491 | 0.73 | MET (0.37) | NR1I2LMNATTRPGRHSP90AA1 | |
| SCHEMBL15832088 | 0.73 | KCNQ3 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1MPO | |
| SCHEMBL14656241 | 0.72 | NPC1 (0.50) | KCNQ3KCNQ2KCNE1KCNQ1TTR | |
| SCHEMBL7182380 | 0.72 | TTR (0.58) | PNLIPHTR2ASLC6A4KCNH2NR1I2 | |
| SCHEMBL18347253 | 0.72 | TTR (0.61) | PNLIPHTR2ASLC6A4LMNATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |