Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 10/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159198 | 0.85 | TSHR (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13812779 | 0.85 | PLA2G4B (0.67) | PLA2G4BRARBPLA2G4A | |
| SCHEMBL13799313 | 0.81 | HDAC3 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13799307 | 0.81 | NR5A1 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14384731 | 0.80 | HDAC1 (0.81) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL809992 | 0.80 | ALOX15 (0.61) | PLA2G4BALOX15ALDH1A1PPARDSMN1; SMN2 | |
| SCHEMBL13799315 | 0.79 | PLA2G4B (0.47) | PLA2G4BRARBPPARDSMN1; SMN2PLA2G4A | |
| SCHEMBL1468538 | 0.78 | FOLH1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15370149 | 0.78 | FOLH1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12130360 | 0.78 | FOLH1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2009-06-25 | — | — | US | disclosed |
| WO-2007133714-A2 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007133714-A2 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STRATOS BIOSYSTEMS, LLC (US) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163380-A1 | ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY | STUB1, SPR, DBI | HDAC3 4059/4885HDAC4 4527/4885HDAC1 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.