Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.74 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 4/20 | 0.43 |
| ▸ | FLT4 | P35916 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322052 | 0.89 | TRPV1 (0.75) | TRPV1VCPIMPDH2FLT1FLT4 | |
| SCHEMBL5349266 | 0.76 | SIRT7 (0.51) | TRPV1SIRT7VCPFLT1FLT4 | |
| SCHEMBL5318816 | 0.76 | SIRT7 (0.51) | TRPV1SIRT7VCPFLT1FLT4 | |
| SCHEMBL5341346 | 0.76 | TRPV1 (0.53) | TRPV1SIRT7VCPFLT1FLT4 | |
| SCHEMBL5319550 | 0.75 | VCP (0.72) | TRPV1SIRT7VCPIMPDH2FLT1 | |
| SCHEMBL5319106 | 0.75 | SIRT7 (0.64) | TRPV1SIRT7VCPMAPTIMPDH2 | |
| SCHEMBL4716401 | 0.73 | TRPV1 (0.48) | TRPV1ALDH1A1LMNAHPGDHTT | |
| SCHEMBL5319683 | 0.70 | KDR (0.78) | TRPV1SIRT7VCPLMNAKDM4E | |
| SCHEMBL29620933 | 0.70 | VCP (0.50) | TRPV1SIRT7VCPMAPTFLT1 | |
| SCHEMBL5316742 | 0.69 | SIRT7 (0.60) | SIRT7VCPHTTIMPDH2FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |