Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521129 | 0.80 | HTR2C (0.48) | HTR2CDRD2HTR2AHDAC3HDAC4 | |
| SCHEMBL5313523 | 0.79 | DRD2 (0.47) | HTR2CDRD2HTR2AHDAC3HDAC4 | |
| SCHEMBL3413391 | 0.76 | HTR2C (0.62) | HTR2CDRD2HTR2AHDAC3HDAC4 | |
| SCHEMBL13005015 | 0.69 | HTR2C (0.70) | HTR2CDRD2HTR2AHTR2BADRA1D | |
| SCHEMBL30065894 | 0.68 | ODC1 (0.41) | ALDH1A1MEN1MAPTALOX15KMT2A | |
| SCHEMBL5315645 | 0.68 | HDAC3 (0.48) | HTR2CDRD2HTR2AHDAC3HDAC4 | |
| SCHEMBL30066045 | 0.66 | KDM4E (0.44) | HRH4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29191747 | 0.65 | ODC1 (0.41) | HTR2CALDH1A1MEN1MAPTALOX15 | |
| SCHEMBL13296368 | 0.64 | TERT (0.43) | ALDH1A1MEN1MAPTALOX15KMT2A | |
| SCHEMBL21922967 | 0.62 | ALDH1A1 (0.44) | HRH4ALDH1A1MEN1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007063385-A2 | SPIROCYCLIC AMINE HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-06-07 | — | — | WO | claimed |