Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CBR1 | P16152 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22567997 | 0.83 | GAA (0.43) | MAP4K4LMNAHSP90AA1MAPTHPGD | |
| SCHEMBL5319900 | 0.82 | RAF1 (0.39) | TRPA1NR1I2LMNATTRPGR | |
| SCHEMBL307909 | 0.78 | MEN1 (0.49) | MAP4K4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1415748 | 0.76 | L3MBTL1 (0.45) | CHRM4TRPA1MAPTHSPB1 | |
| SCHEMBL5317344 | 0.73 | KCNQ3 (0.42) | NR1I2LMNATTRPGRHSP90AA1 | |
| SCHEMBL1437039 | 0.73 | MET (0.45) | METMAP4K4TRPA1HSPB1 | |
| SCHEMBL5319903 | 0.73 | RAF1 (0.42) | CHRM1LMNAHSP90AA1MAPTTBXA2R | |
| SCHEMBL1137007 | 0.71 | MET (0.59) | MET | |
| SCHEMBL27423552 | 0.70 | SMN1; SMN2 (0.56) | MAP4K4LMNAHSP90AA1MAPTHPGD | |
| SCHEMBL26697193 | 0.70 | ALDH1A1 (0.39) | METMAP4K4LMNAHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | claimed |
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |