Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319745 | 0.87 | KMT2A (0.43) | CCR5KCNH2AGTR2MEN1KMT2A | |
| SCHEMBL5314383 | 0.83 | CCR1 (0.39) | NSD2CCR5PLA2G7KCNH2AGTR2 | |
| SCHEMBL5314580 | 0.82 | CCR5 (0.39) | NSD2CCR5PLA2G7AGTR2MEN1 | |
| SCHEMBL5320812 | 0.80 | NSD2 (0.42) | NSD2CCR5AGTR2CCR1MEN1 | |
| SCHEMBL5317011 | 0.78 | KCNH2 (0.47) | KCNH2MEN1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL3127996 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL2967576 | 0.72 | KCNH2 (0.47) | KCNH2KCNJ1 | |
| SCHEMBL3117605 | 0.72 | KCNH2 (0.52) | KCNH2KMT2ACCR3 | |
| SCHEMBL5317641 | 0.69 | MEN1 (0.42) | NSD2CCR5KCNH2MEN1KMT2A | |
| SCHEMBL5317453 | 0.69 | KMT2A (0.48) | KCNH2KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |