Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314383 | 0.88 | CCR1 (0.39) | KMT2AMEN1ALDH1A1POLBCCR5 | |
| SCHEMBL5317628 | 0.87 | NSD2 (0.41) | KMT2AMEN1ALDH1A1POLBCCR5 | |
| SCHEMBL5317011 | 0.87 | KCNH2 (0.47) | MEN1KCNH2HRH1NPC1RAB9A | |
| SCHEMBL5320812 | 0.85 | NSD2 (0.42) | KMT2AMEN1ALDH1A1POLBCCR5 | |
| SCHEMBL5314580 | 0.85 | CCR5 (0.39) | KMT2AMEN1ALDH1A1POLBCCR5 | |
| SCHEMBL5317641 | 0.82 | MEN1 (0.42) | KMT2AMEN1CCR5L3MBTL1KCNJ1 | |
| SCHEMBL5315877 | 0.81 | ABCB1 (0.48) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL4523456 | 0.80 | KCNH2 (0.41) | L3MBTL1KCNJ1KCNH2ARCHRM2 | |
| SCHEMBL5317617 | 0.80 | CCR5 (0.41) | KMT2AMEN1CCR5L3MBTL1OPRM1 | |
| SCHEMBL2967576 | 0.79 | KCNH2 (0.47) | L3MBTL1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |