Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316981 | 0.81 | HTT (0.41) | ALDH1A1CAPN1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL294716 | 0.79 | LMNA (0.43) | ALDH1A1 | |
| SCHEMBL3689317 | 0.78 | CYP2C9 (0.31) | — | |
| SCHEMBL27709106 | 0.77 | LMNA (0.39) | ALDH1A1 | |
| SCHEMBL5314830 | 0.74 | CHRNB2 (0.31) | ALDH1A1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL10967025 | 0.74 | CHRM2 (0.30) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7806653 | 0.73 | GAA (0.39) | ALDH1A1 | |
| SCHEMBL294867 | 0.72 | PPM1B (0.42) | ALDH1A1 | |
| SCHEMBL27351069 | 0.71 | MAPT (0.38) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL5315160 | 0.71 | PPM1B (0.31) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101008020-A | Optically active cyclopropanecarboxamide preparation method | LIYANG FUX CHEMICAL CO LTD (CN) | 2007-08-01 | — | — | CN | disclosed |
| WO-2007069841-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE CYCLOPROPANE CARBOXAMIDE AND DERIVATIVES THEREOF | CHOONGWAE PHARMA CORPORATION (KR) | 2007-06-21 | — | — | WO | disclosed |