Acetone

Acetone

SCHEMBL5318448

CC(C)=O.CCCO.CO.ClCCl

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
ALDH1A1 P00352 7/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 3/20 0.36
CES1 P23141 3/20 0.33
CES2 O00748 2/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FFAR3 O14843 3/20 0.32
HSD17B10 Q99714 2/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL11710899 0.88 LMNA (0.38) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL4797408 0.87 ALDH1A1 (0.43) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL2407511 0.87
Acetone SCHEMBL5145739 0.87 LMNA (0.50) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL10911400 0.83 LMNA (0.46) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL6032202 0.83 ALDH1A1 (0.46) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL2169438 0.83
Acetone SCHEMBL11331997 0.83 ALDH1A1 (0.46) LMNAALDH1A1TDP1TSHRCES1
Acetone SCHEMBL742461 0.83
Propanol SCHEMBL621816 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007064029-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-06-07 WO disclosed
US-6579569-B2 Uses multi-slot coating apparatus to apply multiple liquid layers to moving substrate; high speed, for photographic film and paper products EASTMAN KODAK COMPANY 2003-06-17 US disclosed
US-6534114-B2 Uses multi-slot coating apparatus to apply multiple liquid layers to moving substrate; high speed, for photographic film and paper products EASTMAN KODAK COMPANY 2003-03-18 US disclosed
US-20020160119-A1 Coating method EASTMAN KODAK COMPANY 2002-10-31 US disclosed
US-20020160120-A1 Coating method for modifying adhesion of thin films to substrates EASTMAN KODAK COMPANY 2002-10-31 US disclosed