Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339197 | 0.89 | CASP1 (0.49) | MEN1KMT2ASLC2A1CASP1HSD17B10 | |
| SCHEMBL5341068 | 0.86 | SLC2A2 (0.52) | SLC2A1GRIA1CNR1 | |
| SCHEMBL5318714 | 0.86 | POLB (0.56) | KMT2ASLC2A1CASP1HSD17B10SMN1; SMN2 | |
| SCHEMBL26931775 | 0.85 | GPR119 (0.46) | MEN1KMT2AALOX5SLC2A1HDAC4 | |
| SCHEMBL5337926 | 0.83 | CNR1 (0.58) | MEN1KMT2ASLC2A1HSD17B10HPGD | |
| SCHEMBL5322233 | 0.83 | CNR1 (0.58) | MEN1KMT2ASLC2A1HSD17B10HPGD | |
| SCHEMBL5319613 | 0.82 | SLC2A1 (0.52) | SLC2A1CASP1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL5341500 | 0.82 | KMT2A (0.60) | KMT2ASLC2A1HPGDKCNK3KCNK9 | |
| SCHEMBL5336388 | 0.82 | SLC2A2 (0.47) | SLC2A1KCNK3KCNK9CNR1F2RL1 | |
| SCHEMBL5345220 | 0.81 | KDM4E (0.59) | KMT2ASLC2A1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |