Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559170 | 0.79 | XDH (0.41) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL126342 | 0.79 | ALDH1A1 (0.44) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL31092325 | 0.76 | VCAM1 (0.44) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4812847 | 0.76 | KDM4E (0.44) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1522101 | 0.76 | KDM4E (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27912760 | 0.74 | TDP1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28984045 | 0.73 | S1PR4 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1558545 | 0.73 | S1PR4 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL21808022 | 0.71 | VCAM1 (0.54) | VCAM1ALDH1A1MAPTPIN1TDP1 | |
| SCHEMBL30729474 | 0.71 | VCAM1 (0.54) | VCAM1ALDH1A1MAPTPIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831217-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006069805-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2006-07-06 | — | — | WO | disclosed |