Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 10/20 | 0.46 |
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 7/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314840 | 0.90 | HTR1A (0.53) | KMT2AHTR1ADRD2ALDH1A1KCNH2 | |
| SCHEMBL5315301 | 0.90 | KCNH2 (0.48) | MEN1KMT2AHTR1ADRD2ALDH1A1 | |
| SCHEMBL5316933 | 0.89 | KCNH2 (0.47) | MEN1HTR1ADRD2KCNH2CACNA1B | |
| SCHEMBL5319103 | 0.87 | KCNH2 (0.49) | MEN1HTR1ADRD2ALDH1A1KCNH2 | |
| SCHEMBL5319012 | 0.86 | KCNH2 (0.43) | MEN1KMT2AHTR1ADRD2ALDH1A1 | |
| SCHEMBL5315724 | 0.86 | KCNH2 (0.56) | KMT2AHTR1ADRD2KCNH2CACNA1B | |
| SCHEMBL5316328 | 0.85 | KCNH2 (0.55) | KMT2AHTR1ADRD2KCNH2HTR7 | |
| SCHEMBL5316196 | 0.85 | KCNH2 (0.48) | KMT2AHTR1ADRD2ALDH1A1KCNH2 | |
| SCHEMBL5316515 | 0.84 | KCNH2 (0.45) | MEN1KMT2AHTR1ADRD2ALDH1A1 | |
| SCHEMBL5314570 | 0.83 | HTR1A (0.48) | MEN1KMT2AHTR1ADRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |