Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811728 | 0.78 | — | — | |
| SCHEMBL193502 | 0.77 | CES2 (0.35) | DAO | |
| SCHEMBL21495021 | 0.77 | CES2 (0.35) | DAO | |
| SCHEMBL5147308 | 0.75 | WRN (0.33) | — | |
| SCHEMBL21495048 | 0.75 | ALOX5 (0.40) | DAO | |
| SCHEMBL6865647 | 0.75 | ALOX5 (0.40) | DAO | |
| SCHEMBL1849742 | 0.75 | GABBR2 (0.39) | DAO | |
| SCHEMBL28808975 | 0.71 | — | — | |
| SCHEMBL6128179 | 0.69 | GRM8 (0.37) | — | |
| SCHEMBL14058869 | 0.69 | ALOX5 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836495-A1 | TETRAHYDROPYRROLOTHIAZINE COMPOUNDS | Eli Lilly and Company (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013151832-A1 | TETRAHYDROPYRROLOTHIAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |