Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320835 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL6080168 | 0.78 | HTR6 (0.45) | KDM4ARBP4XDHKDM4EALDH1A1 | |
| SCHEMBL6080287 | 0.77 | KDM4E (0.46) | KDM4AMAPTKDM4ERAB9ATDP1 | |
| SCHEMBL6591671 | 0.74 | KDM4A (0.48) | KDM4AKDM4EPIK3CAALDH1A1RAB9A | |
| SCHEMBL6080409 | 0.73 | KDM4E (0.43) | KDM4AMAPTKDM4ERAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL6079508 | 0.73 | KDM4A (0.47) | KDM4AKDM4EPIK3CAALDH1A1RAB9A | |
| SCHEMBL6592438 | 0.71 | GPR35 (0.51) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL6591710 | 0.69 | TSHR (0.46) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL6591707 | 0.69 | TSHR (0.46) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL6595426 | 0.69 | GAA (0.49) | MAPTLMNAKDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007097697-A1 | THERAPEUTIC QUINOLINE COMPOUNDS THAT ARE 5HT1B MODULATORS | ASTRAZENECA AB (SE) | 2007-08-30 | — | — | WO | claimed |
| WO-2007097697-A1 | THERAPEUTIC QUINOLINE COMPOUNDS THAT ARE 5HT1B MODULATORS | ASTRAZENECA AB (SE) | 2007-08-30 | — | — | WO | disclosed |